Caspases are a family of proteolytic enzymes that play a central role in apoptosis, the regulated process of programmed cell death essential for development, homeostasis and the clearance of damaged ...

Mitochondria are central hubs for cellular stress adaptation, with their function integrated with both apoptosis and autophagy pathways that determine cell fate. Alterations in mitochondrial ...

Mitochondria are involved in apoptosis, necrosis, pyroptosis, and iron death. At present, the research on cell apoptosis is relatively thorough, and the mechanism of mitochondria in it has also been ...

Necrotic cell death is a fundamental biological process, yet the terminal execution mechanisms of necrosis are still not ...

Cell death research has emerged as a cornerstone for understanding the pathogenesis of neurological disorders. Neurons and glial cells in the central ...

An octopus-shaped nanomachine hijacks tumor ATP leakage to power a self-amplifying cycle of membrane damage, drug delivery, and metabolic collapse in cancer cells.