Peptide science has expanded rapidly in recent decades, revealing molecules with intriguing signaling roles that may influence diverse regenerative and organizational processes within an organism.

T cell activation—the process by which these key immune defenders recognize threats and mobilize against them—depends on ...

Extracellular signal-regulated kinase 5 (ERK5), a distinct member of the mitogen-activated protein kinase (MAPK) family, is increasingly recognised for its central role in transducing extracellular ...

The field of extracellular vesicle (EV) biology has rapidly expanded, revealing that these membrane-bound nanoparticles are crucial mediators of ...

This graphic illustrates paracrine adhesion signaling on small extracellular vesicles, which secretes a protein called galectin-3, which promotes endocytosis so the vesicle can be absorbed into the ...

Hypertrophic scarring affects a large proportion of patients following burns, trauma, or surgery and arises from prolonged fibroblast hyperactivity and excessive extracellular matrix accumulation.

Panel A summarizes the conventional model of how oncogenic RAS guanosine triphosphatases (i.e., Kirsten rat sarcoma viral oncogene homologue [KRAS], neuroblastoma RAS viral oncogene homologue [NRAS], ...

This graphic illustrates paracrine adhesion signaling on small extracellular vesicles, which secretes a protein called galectin-3, which promotes endocytosis so the vesicle can be absorbed into the ...

Studies of signal transduction have yielded a wealth of information about the molecules required to transmit signals from the cell surface to the nucleus. Yet it still remains unknown how a signaling ...

Researchers have found that amlodipine, a calcium-channel blocker prescribed to tens of millions of people for high blood ...