Inositol trisphosphate receptors (IP3Rs) are pivotal Ca²⁺ channels embedded in the membrane of the endoplasmic reticulum. Their activation by inositol 1,4,5-trisphosphate (IP3) and Ca²⁺ gives rise to ...

A newly identified protein pair may drive brain cell death in Alzheimer’s, offering a clearer explanation of how the disease progresses.

Researchers in the Perelman School of Medicine at the University of Pennsylvania have identified a cell surface receptor ...

A multinational research team led by researchers at Institute of Science Tokyo, RIKEN, and the University of Toronto has ...

Nerve growth factor receptor TrkA (in green) and co-receptor NRP1 (in purple) are coexpressed in the same nerve cells in mice. Researchers at the NYU Pain Research Center have found a new receptor for ...

T cell activation—the process by which these key immune defenders recognize threats and mobilize against them—depends on ...

Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...

Peptide science has expanded rapidly in recent decades, revealing molecules with intriguing signaling roles that may influence diverse regenerative and organizational processes within an organism.

Scientists discover gut cells that stop mosquitoes from biting after feeding, linking appetite, reproduction, and disease spread.

Researchers have found a new receptor for nerve growth factor that plays an important role in pain signaling, even though it does not signal on its own, according to a new study. The findings hold ...